Paul Friedman, M.D., CEO, joined Incyte in 2001. The following year, he recruited Brian Metcalf, Ph.D., executive vice president and chief drug discovery scientist, to run Incyte's discovery operations.

Paul A. Friedman, M.D.
President and Chief Executive Officer

Paul A. Friedman joined Incyte in 2001 as chief executive officer and a director.

From 1994 to 1998 Dr. Friedman served as president of R & D for the DuPontMerck Pharmaceutical Company and from 1998 to 2001 as the president of DuPont Pharmaceuticals Research Laboratories, a wholly-owned subsidiary of the DuPont Company. From 1991 to 1994, he served as senior vice president at Merck Research Laboratories. Prior to his work at Merck and DuPont, Dr. Friedman was an associate professor of medicine and pharmacology at Harvard Medical School.

Dr. Friedman is a diplomat of the American Board of Internal Medicine, member of the American Society of Pharmacology and Experimental Therapeutics, member of the American Society of Clinical Investigation and member of the American Society of Biological Chemistry. He received his A.B. in biology from Princeton University and his M.D. from Harvard Medical School.

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Brian W. Metcalf, Ph.D.
Executive Vice President and Chief Drug Discovery Scientist

Brian W. Metcalf joined Incyte in February 2002 as executive vice president and chief drug discovery scientist.

From March 2000 to February 2002, Dr. Metcalf served as senior vice president and chief scientific officer of Kosan Biosciences, Incorporated. From December 1983 to March 2000, Dr. Metcalf held a number of executive management positions with SmithKline Beecham, including senior vice president, discovery chemistry and platform technologies. Prior to joining SmithKline Beecham, Dr. Metcalf held positions with Merrell Research Center from 1973 to 1983.

Dr. Metcalf received his B.S. and Ph.D. in organic chemistry from the University of Western Australia. He is also a director of Argonaut Technologies, Inc.

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